PS3 Titles:
Just this last few weeks you can put them on the list of all the normal multiplatform games (such as Bioshock 2, Final Fantasy XIII), but you also have:
Little Big Planet
Heavy Rain
Uncharted 2
MLB 2010 The Show (the best MLB sim ever made)
God of War 3 on the way this month
Valkyria Chronicles
The amazing Q-Games PixelJunk series (Monsters, Racers, Eden and Shooter)
Echochrome and Echoshift
The Ratchet and Clank games
Killzone 2
Fat Princess
Demon's Souls (for the hard core masochistic gamer)
Disgaea 3
Flower
Infamous
Metal Gear Solid 4
The Resistance Series
Warhawk
What you do lose with the PS3 is a nice sense of community, but outside of Mass Effect 2, I've rarely found a SINGLE player experience on the 360 to be as satisfying.
However, give me a hybrid such as Borderlands and I'll choose the 360 version every time because it's easier to chat, etc.
On another note--as a Mac user I'd given up on gaming for the most part--but this new Telltale Games announcement helped. Now that Steam is being ported to the Mac life is looking even better.
Post edited March 04, 2010 by TheMadSpin