Gundato: The problem with that tool is that, to my knowledge, it just says if you have Securom stuff on there. If it IS harmless registry entries (I really don't know), it will still remove those. Does the tool differentiate between saying "We removed a driver" and "We removed stuff we probably shouldn't have bothered putting in the registry in the first place"?
I remember that when I installed Alpha Prime from D2D it installed Securom with it so I used the removal tool. It found Securom components but it couldn't remove them all and prompted a reboot. Afterwards I removed the rest of the components manually and uninstalled the game.
The second time I used the tool I had downloaded and installed both DLCs for Steam's version of Mass Effect. The first DLC asked for a key for online activation but the other one didn't. Also I had installed the EA Download Manager to dowload the second DLC. I read that the EADM installs securom so I uninstalled it then run the removal tool. It showed securom components, I clicked next and it displayed a message saying that I have certain registry entries that contained licenses for my games (I assume it meant the DLC) and I shouldn't erase those. I chose to erase them anyway, rebooted, deleted manually the rest of the entries even though this time the tool said I had removed Securom completely, and rebooted again.
I guess the performance of the removal tool has been inconsistent for me. By now I should have a Securom clean machine and Mass Effect's DLC still shows within my game so I suppose that it didn't need Securom after all. I'll see if Securom installs anything it shouldn't after I get my hands on the games I will order.