hansschmucker: What extensions do you have installed? There are a few resource hogs (like Google Toolbar) that can cause problems. Also, you might want to limit your history to a few days, as searching across months of history data can take a while and since Firefox3 integrated the history into the location bar, that may become a bit of a problem.
JudasIscariot: Just ChatZilla and the Personas extension. I might run CCleaner and clear out my history. Although I ahve tried to run the game in fullscreen mode my ping is ridiculously high and my hardware sucks. I at least managed to eliminate the browser as the problem.
I can say almost without a doubt that the issue is windows 7. I just switched back to XP from Windows 7 and I can play Quake Live now, and I have a buttload of extensions and addons installed on Firefox.