Dawnsinger: Regarding the Vertigo mentioned by Shmacky-McNuts: check the way you hold your head (neck) and your breathing. If you hold your neck in a strained position for longer times (playing games does that to you) seems to "be bad" for the feeling of balance. Maybe it's all the nerves that connect through the neck to the spine and get strained, or the Aorta which might get less throughput and thus your brain starts to suffocate a little
Not particularly strained position of the neck, although I wouldn't discount that completely because blood-pressure to the brain and fluid pressure in the inner ear may indeed affect a person depending on the disorder.
It also may have something to do with the crystals which can build in the labyrinth with some people - constant movement of the head can help move such buildups to benign areas or help break up said accumulation. So frequent slight changes to head position over long periods may indeed help those people.
But on average it's more of an accumulative exposure to stimuli which the brain cannot interpret in synchronisation. The eyes see one thing, the balance centre feels another, the brain doesn't feel it's correct, and the more and more you're exposed to this mismatch the "sicker" you feel. It eventually can trigger lasting headaches, nausea and yes, nystagmus & resulting vertigo. All of these can lead to vomiting and the need to lie down until it passes. Nasty.
It can occur in different parts of a same game. For instance when playing The Long Dark I wasn't being affected much at all for hours of constant gameplay, until my character was caught outside in pitch blackness with a scrolling snow-effect in vision across the screen. With no input of movement other than slight jolting of the steps jarring the snow, and a constant fake snow effect on the screen, it triggered the nastiest full-blown vertigo, headache & eyestrain event I've ever experienced. Took half and hour for me to get back to normal. Had I had a torch or flare in the game at the time, likely I would have been fine, because I would have had more reference for the movement of the character. Head position had nothing to do with this particular situation, but yes I have played other games and found my head tilted to an unnatural angle which may have exacerbated things. :)