HampsterStyle: Nope.
Eh. I'll try using Alcohol 120.
I just tried installing it on my wife's machine from my retail GOTY disks and it worked fine. She's running Win7 x64 with no virtual drives or burning software installed but imgburn. Her only installed optical drive is an IDE one - not sure if the installer doesn't like some SATA drives.
The reason I have a problem installing on mine is because I've always ran my optical drive in an external enclosure since usb 2.0 came out. I like the flexibility of keeping it turned off until needed and using it on other machines. Some copy protection likes to refuse this hardware config even in the absence of virtual drives or cloning software.
As mentioned earlier, since the copy protection is only tied to the installer, you could try installing on your machine with all cloning and virtual drive software uninstalled to see if that works. After install you can just add them back.
Out of curiosity, what is the value of the reg key "ImageState" found at:
"HKEY_LOCAL_MACHINE-SOFTWARE-Microsoft-Windows-CurrentVersion-Setup-State"
(dashes are backslashes because forum was screwing up) right click that key and select "modify" to see it's value.
edit: I attached screenshots