Beyond Good and Evil 2
Starcraft II (Duh for any RTS fan)
Half-Life 2 Episode 3
Portal 2
Braid for PC (If it ever comes)
Star Wars: The Old Republic (if it ends up being microtransactions instead of subscriptions)
Splinter Cell: Convictions (I'm not a huge fan of the whole light/dark mechanic but social stealth intrigues me (Providing the AI isn't moronic like Assassin's Creed))
Aliens: Colonial Marines
Chronicles of Riddick: Assault on Dark Athena
Trine (interesting 2D physics platformer of sorts)
Fez (I want me some vertical platforming)
Resident Evil 5 (for PC of course)
Brutal Legend
Burnout Paradise
Demigod
Alan Wake
Wallace and Gromit’s Grand Adventures
Bioshock 2
Wow, I didn't realize how many games I was looking forward to until I wrote them all down. And I'm sure I even missed a few.

I'm not really waiting for any game, they just about all have alienated or disinterested me. The only games I want are mere rumors..
like Perfect Dark or Marvel Versus Capcom 2 for the XBLA..
otherwise, I am litterally waiting for my copy of Tetris Attack to come in the mail.

I pretty much own a lot of old games, but the one that's been dodging me is Bad Mojo, the roach game, remember?
i've only tried the demo back then and loved the concept. We'll see if gog team can get a hold of their devs or distributors and work something out
Cheers!
Edit: well, i've totally misread the topic title and thought it was a spawn of the wishlist. No current game in development or TBA interest me right now.
Whenever we get a "delete post" option, i'll blast this one :D

Only game I'm really stoked about is Dragon Age:Origins, but if they insist on their asinine DRM scheme, I'll be passing on it.
I'll be buying Mysteries of Westgate when it's finally available (but I don't consider it a 'game' per se, as it's an Adventure Pack for NWN2)
Others that look like I'll likely buy are Aliens RPG, Alpha Protocol, and Divinity 2.
A few that have piqued my interest: Diablo 3, Alan Wake, Age of Decadence, Elemental:War of Magic

I'm currently tracking over 90 PC titles in development, but out of those, I guess these are my top 20 most anticipated (in alphabetical order):
Aliens RPG - from Obsidian Entertainment
Aliens: Colonial Marines - Gearbox Software
Alpha Protocol - Obsidian
Arcania: A Gothic Tale - Spellbound
Batman: Arkham Asylum - Rocksteady Studios
Collapse: Devastated World - Creoteam
Cryostasis: Sleep Of Reason - Action Forms
Dark Void - Airtight Games
Dead Island - Techland (makers of Chrome)
Deus Ex 3 - Eidos Montreal
Earth No More - Recoil Games
FEAR 2: Project Origin - Monolith
Ghostbusters: The Video Game - Terminal Reality
Half-Life 2: Episode 3 - Valve Software
Operation Flashpoint 2: Dragon Rising - Codemasters
The Precursors - Deep Shadows
Project Offset - Offset team
Velvet Assassin - Replay Studios
Warhound - Techland
Wolfenstein - Raven Software
Plenty of others that might turn out to be good games. Dragon Age: Origins, Mass Effect 2, Bioshock 2, Mafia II, Borderlands, Rage and some others are on the back-burner and I may never purchase them if they come with SecuROM DRM. I'd love to see those released on GOG.com, but I know that's never going to happen.

Empire: Total War
Jumpgate Evolution
Star Wars: The Old Republic (Maybe)
Fallout MMO
Company of Heroes 2
Homeworld 3
Civilization V
Supreme Commander 2
Fallout 4

a fantasy world dizzy port

What games have i been waiting for?
GTA4
Fallout3
What games am i waiting for?
Empire Total War
Armed Assault 2
Dragon Age
What games were surprise hits?
Left 4 Dead

Xbox 360: Tales of Vesperia, Star Ocean 4, Final Fantasy XIII, Mass Effect 2
Also waiting for Fable 2, The Last Remnant and Gears of War 2 to drop in price :)
PC: Dragon Age, Hearts of Iron 3
I haven't really been following PC games since I got my 360 though, so I don't really know what's coming out next year.

Age of Decadence
Empire Total war
Dragon Age
Divinity 2
any good rpg which has not been dumbed down to much or has stupid copy protection that hates your computer or has limited installs;

I'm not. I have 0 anticipation for any upcoming titles.

The Longest Journey 3
Thief 4
Mafia 2
Baldur's Gate 3
Disciples 3
a true Fallout 3

How could I forget this? I'm even more stoked since they just released the news that they are getting Mark Hamill and Kevin Conroy from Batman: The Animated Series to voice The Joker and Batman respectively.

The ones I'm really looking forward to:
PC:
Borderlands
Darkfall Online
Dragon Age
Empire: Total War
Gray Matter
Mafia 2 (can't wait for this one)
Rage
Still Life 2
Console:
APB
Prototype
Mass Effect 2
Skate 2 (dont' even skate but I loved the first one)
Fight night 4
Uncharted 2
The UFC game being made, forgot the excat name.

Almost any game which had the Origin logo. I'm afraid this won't happen though :(
[edit]
stupid me, I got that wrong, I thought you meant on Gog.com
Well, for the PC
StarCraft 2 mostly. Any other game I'm not sure if I want it for PC or 360 yet.